Midway via his job, Cees Dekker reinvented himself. Immediately after decades of hardcore physics, he shifted his concentration to ‘nanobiology’ with the flip of the millennium. A expression he coined himself, being a issue of fact.
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[Laughs] ‘It had been undoubtedly a fantastic threat! At time, I was well aware that it could go wrong Which I could develop into a lot less productive, but I just ignored that. Curiosity has always been my strongest driving drive. And fortunately everything worked out.’
Our work was rapidly followed up by Other people, most notably by Phaedon Avouris and colleagues at IBM, who in October 1998 printed their findings on transistors created from solitary- and multi-walled carbon nanotubes in Applied Physics Letters.
2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and to start with ever study on the dynamics DNA supercoils and the discovery of supercoil hopping
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes
‘At the outset we checked out biological techniques that has a physical check out and acted on The idea of your resources we understood. It took a number of years prior to we started out Performing much more on the large Organic challenges. I then began to contact it nanobiology, a phrase that did not exist at enough time.
2011, initial in vitro measurements of transport across a ceesdekker single biomimetic nuclear pore complex; enhancement of multiplexed magnetic tweezers for kilo-molecule experiments; and fixed the system of homology recognition in DNA homologous recombination
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It absolutely was throughout this period that Dekker carried out investigation on magnetic spin devices and on sounds in superconductors and semiconductors.
FtsZ treadmilling is important for Z-ring condensation and septal constriction initiation in bacterial mobile division
2001, discovery of one-electron transistors at home temperature based on nanotubes; realization of initial logic circuits with carbon nanotube gadgets; and discovery in the molecular construction of DNA mend enzymes with AFM
Permit’s to start with look back in the intervening time when you decided to shift your concentrate from superconductivity and nanotubes to biology at the end of the nineties.
Reliable-condition nanopores have demonstrated to generally be a shockingly adaptable probe for single-molecule Investigation of DNA. I will explain several of our current results – precisely DNA knots – and our endeavours to expand the abilities of good-point out nanopores even further more, during the way of one-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.